In 2012, the Ministry of Science and Technology, the Ministry of Health and the Ministry of General Health jointly commenced the construction of the National Clinical Research Center, which was executed in three stages, with the aim of building a total of 32 centers. In June 2013 as the first stage, our center was established as one of the two National Clinical Research Centers in the field of cancer.

Academician Xishan Hao, the director of the Center，has established its organizational and management structure. The Center has formed a collaborative research network within two sub-centers, 20 regional centers and several grass-roots hospitals. We aim to establish a high-level research platform for oncology-transforming medicine.

Research Platform Construction: the Center has established the specifications for the construction of a tissue sample bank for the collection and management of biological samples in accordance with international standards and has formed an internationalized Steering Committee. It has accumulated more than 55,000 tissue specimens, and more than 75,000 blood and body fluid specimens. We also established cancer molecular diagnostics including biochips and next-generation sequencing, and the corresponding bioinformatics technology platforms. The platform acquired pilot unit status for the clinical application of high-throughput sequencing technology from the National Health and Family Planning Commission, which has enabled them to carry out predictions of solid tumor-targeted drug susceptibility, and risk prediction of inherited tumors such as breast cancer and thyroid cancer. The Center has published a core journal: “Chinese Journal of Clinical Oncology”which has been selected as one of the TOP 50 projects of the Chinese Association of Science and Technology Quality Periodicals.In 2018, our English journal “Cancer Biology & Medicine’s impact factor was 4.607, its global ranking was 55th in 222 journals of oncology and 1st in 5 SCI journals of oncology in China.

Academician Xishan Hao is the director of the Center，who established the organizational and management structure of the Center. The Center has been formed collaborative research network within two sub-centers, 20 regional centers and several grass-roots hospitals.

High-Level Talent Team Construction: the Center has been developing its talent team by fostering and importing technical and professional personnel including: 2 outstanding young talents from the National Natural Science Foundation of China, 4 Changjiang Scholars and Professors from the Ministry of Education, 2 talents from National Thousand Talents program, and 1 leading talent from the National Million Plan. In addition, the expert recommended by the Center won the 2016 Chinese Government Friendship Award and was successfully elected as a foreign academician of the Chinese Academy of Engineering in 2017.

High-Level Talent Team Construction : the Center has fostering and importing 2 outstanding young talents of the National Natural Science Foundation of China, 4 Changjiang Scholars and Professors of the Ministry of Education, 2 talents of National Thousand Talents program, 1 leading talent of National Million Plan. In additions, the expert recommended by the Center won the 2016 Chinese Government Friendship Award and were successfully elected as a foreign academician of the Chinese Academy of Engineering in 2017.

Scientific Research Construction: since the establishment of the center, it has attracted 285 scientific research projects at provincial and ministerial level, and the scientific research funding has reached 159.333 million yuan, including 4 National Key R&D (Research and Development) Plans, 3 National Science and Technology Support Plans, 2 Major International Cooperation Projects from the National Natural Science Foundation, 1 Outstanding Youth Project, and 1 Sino-Canadian Cooperation Project. More than 1,000 papers have been published in SCI journals, 28 papers in “IF≥10 papers”, and we have won 25 technology awards at provincial and ministerial level. We have led/participated in 73 multi-center clinical studies and undertaken more than 70 projects to develop the related guidelines.

The Center will further implement the National Innovation-driven Development Strategy, the “13th Five-year Plan for Technology and Innovation”, the “Plan of Health China 2030”, and the “13th Five-Year Plan for Health and Science & Technology Innovation”. In accordance with the requirements of the “Five-Year Development Plan of the National Center for Clinical Research (2017-2021)”, which was jointly formulated by the Ministry of Science and Technology, the National Health and Family Planning Commission, the Military Commission's Logistics Support Department and the General Administration of Food and Drug Administration, the Center will actively promote its development, improve its organizational and network structure, optimize its allocation of resources, and improve its operational management system.